PTPN7 Mouse Monoclonal Antibody [Clone ID: OTI3B10]
Specifications
| Product Data | |
| Clone Name | OTI3B10 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | WB 1:500~2000, IF 1:100 |
| Reactivity | Dog, Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human PTPN7(NP_542155) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 44.8 kDa |
| Gene Name | protein tyrosine phosphatase non-receptor type 7 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq |
| Synonyms | BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | MAPK signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3B10" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA503714 | PTPN7 (HePTP) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) | 100 ul |
$447.00
|
|
| TA503714AM | PTPN7 (HePTP) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10), Biotinylated | 100 ul |
$509.00
|
|
| TA503714BM | PTPN7 (HePTP) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10), HRP conjugated | 100 ul |
$509.00
|
|
| TA503714S | PTPN7 (HePTP) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) | 30 ul |
$200.00
|
|
Citations
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