Apc2 (ANAPC2) Mouse Monoclonal Antibody [Clone ID: OTI1B12]

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SKU
CF503404
Carrier-free (BSA/glycerol-free) ANAPC2 mouse monoclonal antibody, clone OTI1B12 (formerly 1B12)
  $620.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name OTI1B12
Application IF, WB
Recommended Dilution WB 1:500~2000, IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ANAPC2(NP_037498) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 93.6 kDa
Gene Name anaphase promoting complex subunit 2
Database Link
Background A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. provided by RefSeq, Jul 2008
Synonyms APC2
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
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Other "OTI1B12" antibodies (4)
SKU Description Size Price
TA503404 ANAPC2 (Apc2) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12) 100 ul
$447.00
TA503404AM ANAPC2 (Apc2) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12), Biotinylated 100 ul
$509.00
TA503404BM ANAPC2 (Apc2) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12), HRP conjugated 100 ul
$509.00
TA503404S ANAPC2 (Apc2) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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