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PDF Mouse Monoclonal Antibody [Clone ID: OTI3F3]

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SKU
CF502988
Carrier-free (BSA/glycerol-free) PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "PDF or NM_022341" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3F3
Application FC, IF, WB
Recommended Dilution WB 1:500~2000, IF 1:100, FLOW 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PDF (NP_071736) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 19.4 kDa
Gene Name peptide deformylase, mitochondrial
Database Link
Background Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. provided by RefSeq
Reference Data
Protein Categories Intracellular Proteins
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Other "OTI3F3" antibodies (4)
SKU Description Size Price
TA502988 PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3) 100 ul
$447.00
TA502988AM PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3), Biotinylated 100 ul
$509.00
TA502988BM PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3), HRP conjugated 100 ul
$509.00
TA502988S PDF mouse monoclonal antibody, clone OTI3F3 (formerly 3F3) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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