OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

ALDH1A3 Mouse Monoclonal Antibody [Clone ID: OTI4E8]

  • Product Brand Image
Be the first to review this product
SKU
CF502841
Carrier-free (BSA/glycerol-free) ALDH1A3 mouse monoclonal antibody, clone OTI4E8 (formerly 4E8)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
Bulk/Customize

View other "ALDH1A3 or NM_000693" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4E8
Application FC, WB
Recommended Dilution WB 1:200~2000, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-100 and 413-512 of human ALDH1A3 (NP_000648) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 55.9 kDa
Gene Name aldehyde dehydrogenase 1 family member A3
Database Link
Background Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form. provided by RefSeq, Jul 2008
Synonyms ALDH1A6; ALDH6; MCOP8; RALDH3
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "OTI4E8" antibodies (4)
SKU Description Size Price
TA502841 ALDH1A3 mouse monoclonal antibody, clone OTI4E8 (formerly 4E8) 100 ul
$447.00
TA502841AM ALDH1A3 mouse monoclonal antibody, clone 4E8, Biotinylated 100 ul
$509.00
TA502841BM ALDH1A3 mouse monoclonal antibody, clone 4E8, HRP conjugated 100 ul
$509.00
TA502841S ALDH1A3 mouse monoclonal antibody, clone OTI4E8 (formerly 4E8) 30 ul
$200.00

file-alt Citations

ALDH1A3-regulated long non-coding RNA NRAD1 is a potential novel target for triple-negative breast tumors and cancer stem cells
Vidovic, Huynh, Konda et al
Cell Death Differ. (2019) 27 (1), 363-378 DOI: 10.1038/s41418-019-0362-1
AI Summary: OriGene’s anti-ALDH1A3 antibody (clone 4E8) was used to confirm ALDH1A3 knockdown or overexpression by western blotting and qPCR in this study investigating the role of NRAD1 in triple-negative breast cancer and cancer stem cells.
Snippet: To discover novel therapeutic targets for triple-negative breast cancer (TNBC) and cancer stem cells (CSCs), we screened long non-coding RNAs (lncRNAs) most enriched in TNBCs for high expression in CSCs defined by high Aldefluor activity and associated with worse patient;- Knockdown or overexpression of ALDH1A3 was confirmed by QPCR and western blotting (anti-ALDH1A3, Origene, clone 4E8). …
WB
Establishment of MAGEC2-knockout cells and functional investigation of MAGEC2 in tumor cells
Wang, Song, Guo et al
Cancer Sci. (2016) 107 (12), 1888-1897 DOI: 10.1111/cas.13082
AI Summary: OriGene products, specifically the anti-ALDH1A3 and anti-BID antibodies, were used in this study to detect and analyze protein expression changes in MAGEC2-knockout tumor cells.
Snippet: Commercial antibodies used in this study were as follows: anti‐GAPDH (Bioworld, St Louis, MO, USA), anti‐NES (Novus, littleton, CO, USA), anti‐ALDH1A3 (Origene, Rockville, MD, USA), anti‐SERPINB2 (Bioworld), anti‐HTRA2 (Proteintech, Rosemont, IL, USA), anti‐BID (Origene),
FigureFigureFigure
Showing 1-2 of 2 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products