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FGFR2 Mouse Monoclonal Antibody [Clone ID: OTI5F7]

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SKU
CF502829
Carrier-free (BSA/glycerol-free) FGFR2 mouse monoclonal antibody, clone OTI5F7 (formerly 5F7)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "FGFR2 or NM_000141" antibodies

Specifications
Specifications
Product Data
Clone Name OTI5F7
Application FC, IF
Recommended Dilution IF 1:100
FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FGFR2 (NP_000132) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 89.7 kDa
Gene Name fibroblast growth factor receptor 2
Database Link
Background The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. provided by RefSeq
Synonyms BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25
Reference Data
Protein Categories ADC Targets, Cancer: Gastrointestinal, CD Markers, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins
Protein Families Druggable Genome, Protein Kinase, Secreted Protein, Transmembrane
Protein Pathways Endocytosis, MAPK signaling pathway, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
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Other "OTI5F7" antibodies (5)
SKU Description Size Price
TA502829 FGFR2 mouse monoclonal antibody, clone OTI5F7 (formerly 5F7) 100 ul
$447.00
TA502829AM FGFR2 mouse monoclonal antibody, clone 5F7, Biotinylated 100 ul
$509.00
TA502829BM FGFR2 mouse monoclonal antibody, clone 5F7, HRP conjugated 100 ul
$509.00
TA502829S FGFR2 mouse monoclonal antibody, clone OTI5F7 (formerly 5F7) 30 ul
$200.00
TA600367 FGFR2 mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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