ATP6V1B1 Mouse Monoclonal Antibody [Clone ID: OTI1H6]

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SKU
CF502677
Carrier-free (BSA/glycerol-free) ATP6V1B1 mouse monoclonal antibody, clone OTI1H6 (formerly 1H6)
  $620.00
3 Days*
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Specifications
Specifications
Product Data
Clone Name OTI1H6
Application FC, IF, IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human ATP6V1B1 (NP_001683) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 56.7 kDa
Gene Name ATPase H+ transporting V1 subunit B1
Database Link
Background This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. provided by RefSeq
Synonyms ATP6B1; RTA1B; VATB; VMA2; VPP3
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection
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Other "OTI1H6" antibodies (4)
SKU Description Size Price
TA502677 ATP6V1B1 mouse monoclonal antibody, clone OTI1H6 (formerly 1H6) 100 ul
$447.00
TA502677AM ATP6V1B1 mouse monoclonal antibody, clone OTI1H6 (formerly 1H6), Biotinylated 100 ul
$509.00
TA502677BM ATP6V1B1 mouse monoclonal antibody, clone OTI1H6 (formerly 1H6), HRP conjugated 100 ul
$509.00
TA502677S ATP6V1B1 mouse monoclonal antibody, clone OTI1H6 (formerly 1H6) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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