SAMHD1 Mouse Monoclonal Antibody [Clone ID: OTI2B5]
SKU
CF502085
Carrier-free (BSA/glycerol-free) SAMHD1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI2B5 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 72 kDa |
| Gene Name | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 |
| Database Link | |
| Background | This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. provided by RefSeq, Mar 2010 |
| Synonyms | CHBL2; DCIP; HDDC1; MOP-5; SBBI88 |
| Reference Data | |
| Protein Categories | Immune system diseases, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2B5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA502085 | SAMHD1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5) | 100 ul |
$447.00
|
|
| TA502085AM | SAMHD1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5), Biotinylated | 100 ul |
$509.00
|
|
| TA502085BM | SAMHD1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5), HRP conjugated | 100 ul |
$509.00
|
|
| TA502085S | SAMHD1 mouse monoclonal antibody, clone OTI2B5 (formerly 2B5) | 30 ul |
$200.00
|
|
Citations
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation
Hu, Li, Xu et al
PLoS Genet. (2015) 11 (7), e1005367 DOI: 10.1371/journal.pgen.1005367
Hu, Li, Xu et al
PLoS Genet. (2015) 11 (7), e1005367 DOI: 10.1371/journal.pgen.1005367
Cited by 123
AI Summary: OriGene’s anti-SAMHD1 antibody (TA502085) was used in this study to detect SAMHD1 protein levels, helping to elucidate its role in inhibiting LINE-1 retrotransposition through the promotion of stress granule formation.
Snippet: Anti-Myc antibody (CST2276) was purchased from Cell Signaling, anti-HA.11 antibody (MMS-101P) from Covance, anti-SAMHD1 antibody (TA502085) from ORIGENE, rabbit anti-G3BP1 antibody (13057-2-AP), rabbit anti-TIA1 (12133-2-AP), rabbit anti eIF4G (15704-1-AP), and anti-actin antibody (60008-1-Ig) from Proteintech, mouse anti-G3BP1 antibody (clone 14E5-G9, 05–1938) from Millipore
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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