HDAC6 Mouse Monoclonal Antibody [Clone ID: OTI4C5]

SKU CF502030

Carrier-free (BSA/glycerol-free) HDAC6 mouse monoclonal antibody, clone OTI4C5 (formerly 4C5)

Product Data

• Clone Name: OTI4C5
• Application: FC, IF, IHC, WB
• Recommended Dilution: WB 1:1000~2000, IF 1:100, FLOW 1:100, IHC 1:150
• Reactivity: Dog, Human, Monkey, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human HDAC6 (NP_006035) produced in HEK293T cell.
• Buffer: Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
• Reconstitution Method: For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Ambient
• Predicted Protein Size: 131.2 kDa
• Gene Name: histone deacetylase 6
• Database Link:
  NP_006035
  Q9UBN7
• Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq]
• Synonyms: CPBHM; HD6; JM21; PPP1R90

Reference Data

• Protein Families: Druggable Genome, Transcription Factors