ERCC1 Mouse Monoclonal Antibody [Clone ID: OTI3E1]
SKU
CF501766
Carrier-free (BSA/glycerol-free) ERCC1 mouse monoclonal antibody, clone OTI3E1 (formerly 3E1)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3E1 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:2000, FLOW 1:100 |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human ERCC1 (NP_973730) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 32.4 kDa |
| Gene Name | ERCC excision repair 1, endonuclease non-catalytic subunit |
| Database Link | |
| Background | The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. provided by RefSeq |
| Synonyms | COFS4; RAD10; UV20 |
| Reference Data | |
| Protein Categories | Growth Factors, Intracellular Proteins |
| Protein Families | Druggable Genome |
| Protein Pathways | Nucleotide excision repair |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3E1" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA501766 | Anti-ERCC1 mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) | 100 ul |
$447.00
|
|
| TA501766AM | ERCC1 mouse monoclonal antibody, clone 3E1, Biotinylated | 100 ul |
$509.00
|
|
| TA501766BM | ERCC1 mouse monoclonal antibody, clone 3E1, HRP conjugated | 100 ul |
$509.00
|
|
| TA501766S | Anti-ERCC1 mouse monoclonal antibody, clone OTI3E1 (formerly 3E1) | 30 ul |
$200.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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