QPRT Mouse Monoclonal Antibody [Clone ID: OTI4E5]
SKU
CF501519
Carrier-free (BSA/glycerol-free) QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI4E5 |
|---|---|
| Application | FC, IF, WB |
| Recommended Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 30.6 kDa |
| Gene Name | quinolinate phosphoribosyltransferase |
| Database Link | |
| Background | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. provided by RefSeq. COMPLETENESS: complete on the 3' end. |
| Synonyms | HEL-S-90n; QPRTase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Metabolic pathways, Nicotinate and nicotinamide metabolism |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI4E5" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA501519 | Anti-QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) | 100 ul |
$447.00
|
|
| TA501519AM | Anti-QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5), Biotinylated | 100 ul |
$509.00
|
|
| TA501519BM | Anti-QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5), HRP conjugated | 100 ul |
$509.00
|
|
| TA501519S | Anti-QPRT mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) | 30 ul |
$200.00
|
|
Citations
Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes
Wogram, Sümpelmann, Dong et al
Immunity (2024) 57 (9), 2216-2231.e11 DOI: 10.1016/j.immuni.2024.07.019
Wogram, Sümpelmann, Dong et al
Immunity (2024) 57 (9), 2216-2231.e11 DOI: 10.1016/j.immuni.2024.07.019
Cited by 9
AI Summary: OriGene contributed to this study by providing the QPRT primary antibody (mouse, #TA501519S), which was used for histological analysis of microglial phagosomes.
Snippet: …Primary antibodies used in this study were QPRT (mouse, Origene, #TA501519S, 1:70), IBA1 (Abcam, ab283319, mouse, 1:1000), CD68 (BioRad, MCA1815T, mouse, 1:70;Lifespan Biosciences, # LS-C313145-100, rabbit, 1:70;and CD68 ABIN3044053 for paraffin sections, rabbit, 1:400), TUJ1 (BioLegend, # 801201, mouse, 1:1000) and GFAP (Abcam, ab53554-100ug, goat, 1:1000), SV2A (Thermo Fisher Scientific Cat# PA5-113833, 1:100, rabbit), LAMP1 (, 1:100, mouse), RAB7 (Cell Signaling, Cat
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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