IGF2BP2 Mouse Monoclonal Antibody [Clone ID: OTI3F9]
SKU
CF501269
Carrier-free (BSA/glycerol-free) IGF2BP2 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9)
$620.00
3 Days*
Specifications
| Product Data | |
| Clone Name | OTI3F9 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100 |
| Reactivity | Dog, Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human IGF2BP2 (NP_006333) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 65.9 kDa |
| Gene Name | insulin like growth factor 2 mRNA binding protein 2 |
| Database Link | |
| Background | This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. provided by RefSeq |
| Synonyms | IMP-2; IMP2; VICKZ2 |
| Reference Data | |
| Protein Categories | Cytokines, Diabetes, Growth Factors, Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI3F9" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA501269 | Anti-IGF2BP2 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9) | 100 ul |
$447.00
|
|
| TA501269AM | Anti-IGF2BP2 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9), Biotinylated | 100 ul |
$509.00
|
|
| TA501269BM | Anti-IGF2BP2 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9), HRP conjugated | 100 ul |
$509.00
|
|
| TA501269S | Anti-IGF2BP2 mouse monoclonal antibody, clone OTI3F9 (formerly 3F9) | 30 ul |
$200.00
|
|
Citations
IMP2 enhances M2 macrophage polarization via LKB1-AMPK-mediated mitochondrial dynamics and fatty acid β-oxidation to ameliorate diabetic osteoporosis
Li, Cui, Ji et al
Cell Mol Life Sci (2026) 83 (1) DOI: 10.1007/s00018-026-06093-5
Li, Cui, Ji et al
Cell Mol Life Sci (2026) 83 (1) DOI: 10.1007/s00018-026-06093-5
Cited by 1
AI Summary: In this study, the OriGene Anti-IMP2 antibody (TA501269) was used to detect IMP2 protein expression, helping to elucidate the role of IMP2 in regulating M2 macrophage polarization and its impact on diabetic osteoporosis.
Snippet: (HA72289 HA601453, Huabio), Anti-IMP2 antibody (A5189, ABclonal;TA501269, ORIGENE), Anti-MFN1 antibody (A21293, ABclonal), Anti-CPT1A antibody (HA722081, Huabio), Goat anti-rabbit IgG H&L (ab150081, Abcam), Goat anti-mouse IgG H&L (ab150119, Abcam), DAPI (ab104139,
Histone lactylation contributes to neuropathic pain by facilitating m6A reader protein IGF2BP2 expression in DRG sensory neurons
Wang, Xie, Yang et al
J Neurosci (2025)
Wang, Xie, Yang et al
J Neurosci (2025)
IGF2BP2 stabilized by USP7 promotes cancer-associated fibroblast activation and attenuates gemcitabine sensitivity in PDAC
Ge, Zhu, Liu et al
Cell Rep (2025) 44 (11), 116476 DOI: 10.1016/j.celrep.2025.116476
Ge, Zhu, Liu et al
Cell Rep (2025) 44 (11), 116476 DOI: 10.1016/j.celrep.2025.116476
Cited by 2
AI Summary: In this study, the OriGene IGF2BP2 Mouse Monoclonal Antibody (Cat.: TA501269) was used to detect and analyze IGF2BP2 protein levels, contributing to the investigation of its stabilization by USP7 and its role in cancer-associated fibroblast activation and chemoresistance in pancreatic ductal adenocarcinoma.
RNA-binding protein IGF2BP2/IMP2 is required for laminin-β2 mRNA translation and is modulated by glucose concentration
Schaeffer, Hansen, Morris et al
Am. J. Physiol. Renal Physiol. (2012) 303 (1), F75-82 DOI: 10.1152/ajprenal.00185.2012
Schaeffer, Hansen, Morris et al
Am. J. Physiol. Renal Physiol. (2012) 303 (1), F75-82 DOI: 10.1152/ajprenal.00185.2012
Cited by 50
AI Summary: OriGene contributed to this study by providing the IMP2 antibody (TA501269, 3F9), which was used for immunoblotting to investigate the role of IMP2 in regulating LAMB2 translation.
Snippet: The following antibodies were used: IMP2 (TA501269, 3F9, Origene, Rockville, MD) for immunobloting (IB) or RN008P (MBL, Woburn, MA) for RNA immunoprecipitation;LAMB2 [C4 (IB) or D5 immunofluorescence (IF)], a monoclonal anti-laminin β2 developed by Dr. J. Sanes
Showing 1-4 of 4 papers.
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