BTK Mouse Monoclonal Antibody [Clone ID: OTI12D4]
Specifications
| Product Data | |
| Clone Name | OTI12D4 |
|---|---|
| Application | FC, IF, IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 76.1 kDa |
| Gene Name | Bruton tyrosine kinase |
| Database Link | |
| Background | The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes,and associated with a failure of Ig heavy chain rearrangement. |
| Synonyms | AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA |
| Reference Data | |
| Protein Categories | Cytokines, Endocrine and metabolic diseases, Enzyme: Kinases, Immune system diseases, Intracellular Proteins |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI12D4" antibodies (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA501090 | Anti-BTK mouse monoclonal antibody, clone OTI12D4 (formerly 12D4) | 100 ul |
$447.00
|
|
| TA501090AM | Anti-BTK mouse monoclonal antibody, clone OTI12D4 (formerly 12D4), Biotinylated | 100 ul |
$509.00
|
|
| TA501090BM | Anti-BTK mouse monoclonal antibody, clone OTI12D4 (formerly 12D4), HRP conjugated | 100 ul |
$509.00
|
|
| TA501090S | Anti-BTK mouse monoclonal antibody, clone OTI12D4 (formerly 12D4) | 30 ul |
$200.00
|
|
| TA600512 | purified BTK mouse monoclonal capture antibody, validated for Luminex assays | 100 ug |
$458.00
|
|
| TA700509 | purified BTK biotinylated mouse monoclonal detection antibody, validated for Luminex assays | 50 ug |
$494.00
|
|
Citations
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