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GBE1 Mouse Monoclonal Antibody [Clone ID: OTI3B4]

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SKU
CF500801
Carrier-free (BSA/glycerol-free) GBE1 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
4 Weeks*
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View other "GBE1 or NM_000158" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3B4
Application IP, WB
Recommended Dilution WB 1:2000, IP 2ug/500ul
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Full length human recombinant protein of human GBE1 (NP_000149) produced in HEK293T cell.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 80.3 kDa
Gene Name 1,4-alpha-glucan branching enzyme 1
Database Link
Background The protein encoded by this gene is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease). provided by RefSeq
Synonyms APBD; GBE; GSD4
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Starch and sucrose metabolism
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Other "OTI3B4" antibodies (4)
SKU Description Size Price
TA500801 GBE1 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100 ul
$447.00
TA500801AM GBE1 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4), Biotinylated 100 ul
$509.00
TA500801BM GBE1 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4), HRP conjugated 100 ul
$509.00
TA500801S GBE1 mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 30 ul
$200.00

file-alt Citations

WTAP/IGF2BP3-mediated GBE1 expression accelerates the proliferation and enhances stemness in pancreatic cancer cells via upregulating c-Myc
Jin, Yao, Fu et al
Cell Mol Biol Lett (2024) 29 (1), 97 DOI: 10.1186/s11658-024-00611-8
Cited by 16
AI Summary: OriGene’s GBE1 antibody (TA500801) was used for immunohistochemistry staining to assess GBE1 protein expression in tumor tissues in this study.
Snippet: stochemistry (IHC) The nude mice tumor tissues were fixed and then subjected to paraffin-embedded. Immunohistochemistry staining was conducted as previously described [13]. Antibodies including GBE1 (Origene, TA500801), c-Myc (Abcam, ab32072) and Ki-67 (CST, 12202) were used for IHC staining. Image J was used to analyzed the IHC staining of GBE1, c-Myc and Ki67, which was shown as integrated optic
FigureFigureFigure
IHC
Generation of a novel mouse model that recapitulates early and adult onset glycogenosis type IV
Akman, Sheiko, Tay et al
Hum Mol Genet (2011) 20 (22), 4430-9 DOI: 10.1093/hmg/ddr371
Cited by 42
AI Summary: OriGene products, specifically the Gbe1 (NM_010263) cDNA clone and anti-GBE1 antibody (TA500276), were used in this study to analyze GBE1 gene expression and protein levels in the novel mouse models of glycogen storage disease type IV.
Showing 1-2 of 2 papers.
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