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MEK4 (MAP2K4) Mouse Monoclonal Antibody [Clone ID: OTI2E4]

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SKU
CF500412
Carrier-free (BSA/glycerol-free) MAP2K4 mouse monoclonal antibody, clone OTI2E4 (formerly 2E4)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
4 Weeks*
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View other "MEK4 or NM_003010" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2E4
Application IF, IHC
Recommended Dilution IHC 1:50
IF 1:100
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full-length protein expressed in 293T cell transfected with human MAP2K4 expression vector
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 44.3 kDa
Gene Name mitogen-activated protein kinase kinase 4
Database Link
Background This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver.
Synonyms JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1
Reference Data
Protein Categories Enzyme: Kinases, Intracellular Proteins
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway
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Other "OTI2E4" antibodies (4)
SKU Description Size Price
TA500412 Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) 100 ul
$447.00
TA500412AM Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), Biotinylated 100 ul
$509.00
TA500412BM Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4), HRP conjugated 100 ul
$509.00
TA500412S Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI2E4 (formerly 2E4) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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