FGF2 Mouse Monoclonal Antibody [Clone ID: OTI2H11]
Specifications
| Product Data | |
| Clone Name | OTI2H11 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:500~2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 10-155 of human bFGF (NP_001997) produced in E.coli. |
| Buffer | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Predicted Protein Size | 30.6 kDa |
| Gene Name | fibroblast growth factor 2 |
| Database Link | |
| Background | BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. |
| Synonyms | BFGF; FGF-2; FGFB; HBGF-2 |
| Reference Data | |
| Protein Categories | Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "OTI2H11" antibodies (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| TA500013 | bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11) | 100 ul |
$447.00
|
|
| TA500013AM | bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11), Biotinylated | 100 ul |
$509.00
|
|
| TA500013BM | bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11), HRP conjugated | 100 ul |
$509.00
|
|
| TA500013S | bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11) | 30 ul |
$200.00
|
|
Citations
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