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STAT5A Mouse Monoclonal Antibody [Clone ID: OTI4H1]

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SKU
CF500006
Carrier-free (BSA/glycerol-free) Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1)
Size:
100 ug
Formulation:
Carrier-free Standard
Conjugation:
Unconjugated
  $620.00
3 Days*
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View other "STAT5A or NM_003152" antibodies

Specifications
Specifications
Product Data
Clone Name OTI4H1
Application IHC, WB
Recommended Dilution WB 1:500~2000
IHC 1:50
Reactivity Human, Mouse, Rat
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 2-104 of human Stat5a (NP_003143) produced in E.coli.
Buffer Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Predicted Protein Size 90.5 kDa
Gene Name signal transducer and activator of transcription 5A
Database Link
Background Stat5a is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, and thrombopoietin. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Synonyms MGF; STAT5
Note WB application:Only overexpression results are guaranteed, not endogenous
Reference Data
Protein Categories Cytokines, Growth Factors, Intracellular Proteins, Transciption Factors
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors
Protein Pathways Acute myeloid leukemia, Chronic myeloid leukemia, ErbB signaling pathway, Jak-STAT signaling pathway, Pathways in cancer
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Other "OTI4H1" antibodies (6)
SKU Description Size Price
TA500006 Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 100 ul
$447.00
TA500006AM Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1), Biotinylated 100 ul
$509.00
TA500006BM Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1), HRP conjugated 100 ul
$509.00
TA500006S Stat5a mouse monoclonal antibody, clone OTI4H1 (formerly 4H1) 30 ul
$200.00
TA600173 STAT5A mouse monoclonal capture antibody, validated for ELISA and Luminex assays 100 ug
$458.00
TA700170 STAT5A biotinylated mouse monoclonal detection antibody, validated for ELISA and Luminex assays 50 ug
$494.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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