CX3CL1 Chicken Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | Immunohistochemistry on Frozen Sections: 1 μg/ml (1/200). Lower working concentration combined with longer incubation time (e.g. > 2 hours at RT) and choice of blocking reagent and secondary antibody may improve your results. Recommended Positive Control: Rat brain. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Chicken |
| Clonality | Polyclonal |
| Immunogen | Synthetic C-terminal peptide coupled to carrier protein. The immunizing sequence is > 90% identical with the corresponding mouse and rat sequences. |
| Specificity | The antibody reacts with Fractalkine. |
| Buffer | PBS, pH 7.2 State: Aff - Purified State: Lyophilized purified IgY fraction Preservative: 0.01% Sodium Azide |
| Reconstitution Method | Restore with 0.5 ml distilled water to make stock solution. |
| Concentration | 0.2 mg/ml (after reconstitution) |
| Purification | Affinity Chromatography against peptide coupled to Sepharose |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | C-X3-C motif chemokine ligand 1 |
| Database Link | |
| Background | Fractalkine is a chemokine present in endothelial cells from several tissues, including brain, liver, and kidney. A high level of fractalkine has also been described in neurons from different regions of the mouse brain. It is the only member of the CX(3)C class of chemokines. Fractalkine contains a chemokine domain (CDF) attached to a membranespanning domain via a mucin-like stalk. However, fractalkine can also be proteolytically cleaved from its membrane-spanning domain to release a freely diffusible form. Fractalkine attracts and immobilizes leukocytes by binding to its receptor, CX(3)CR(1). |
| Synonyms | Neurotactin, FKN, NTT, SCYD1 |
| Reference Data | |
| Protein Categories | Chemokines, Cytokines, Growth Factors, Membrane Proteins, Secreated Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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