beta 2 Microglobulin (B2M) Mouse Monoclonal Antibody [Clone ID: 2213]

SKU
BM603
beta 2 Microglobulin (B2M) mouse monoclonal antibody, clone 2213, Purified
  $770.00
5 Days*
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Specifications
Specifications
Product Data
Clone Name 2213
Application ELISA, IHC, R
Recommended Dilution Immunohistochemistry on frozen sections.
ELISA.
RIA.
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Highly pure β-2-Microglobulin from human urine
Specificity The antibody recognizes human beta 2 microglobulin.
Other species not tested.
Buffer PBS, pH 8.0, containing 10% glycerol and 0.05% sodium azide
State: Purified
State: Liquid purified IgG
Concentration lot specific
Purification Protein A chromatography
Conjugation Unconjugated
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name beta-2-microglobulin
Database Link
Background B2M is the beta chain of MHC class I molecules. The precursor protein has a molecular weight of apprximately 14 kDa and is 119 amino acids in length.
Synonyms B2M, Beta-2 microglobulin, Beta 2 microglobulin
Reference Data
Protein Categories Cancer: Haematopoietic and Lymphoid, Cardiovascular diseases, Cytokines, Nervous system: Neurodegenerative diseases, Secreated Proteins
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Documents
Resources

file-alt Citations

Epigenetic alterations in Sjögren's syndrome patient saliva
Karagianni, Goules, Tzioufas
Clin. Exp. Immunol. (2020)
Cited by 8
AI Summary: OriGene's 5-hydroxymethylated Cytosine antibody (AM33116PU-N) was used for DNA immunoprecipitation to analyze epigenetic modifications in saliva samples from Sjögren's syndrome patients in this study.
Snippet: CATCCAATCCAAATGCGGCA-3. DNA immunoprecipitation was performed using an antibody specifically recognizing 5-hydroxymethylated Cytosine (Origene, AM33116PU-N), as previously described (8). Statistical analysis has been performed using GraphPad Prism
IP
WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer
Poujade, Mannion, Brittain et al
Br. J. Cancer (2018)
AI Summary: OriGene's TissueScan breast cancer microarray plates were used to analyze gene expression levels in breast cancer tissue samples, enabling the study to assess WSB-1 transcript levels in relation to metastatic potential.
Snippet: Transcript levels in TissueScan breast microarray plates (panels I, II, IV) (OriGene) were analysed using TaqMan qPCR SsoAdvanced Universal Probes for WSB1 (qHsaCIP0050519), CA9 (qHsaCIP0031395) (BioRad), and B2M (4326319E) (Applied Biosystems)
Dexamethasone nanowafer as an effective therapy for dry eye disease
Coursey, Henriksson, Marcano et al
J Control Release (2015) 213, 168-174 DOI: 10.1016/j.jconrel.2015.07.007
Cited by 104
AI Summary: In this study, OriGene’s TNF-α TaqMan probe (MP217748) was used for real-time PCR analysis to measure inflammatory gene expression, helping to evaluate the anti-inflammatory efficacy of the dexamethasone nanowafer therapy for dry eye disease.
Snippet: Real time PCR was performed using specific Taqman probes for MMP-3 ((Mmp3) (Mm00440295_m1)), CCL-5 ((Ccl5) (Mm00445235-m1)), CXCL-10 (Cxcl10) (Mm01302427_m1), TNF-α ((Tnfa) (OriGene MP217748)), and IFN-γ ((Ifng) (Mm00801778_m1)) genes (Taqman ... Cite SaveSaving
Showing 1-3 of 3 papers.
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