Insulin (INS) Mouse Monoclonal Antibody [Clone ID: E2E3]
Specifications
| Product Data | |
| Clone Name | E2E3 |
|---|---|
| Application | ELISA, IHC, WB |
| Recommended Dilution | ELISA. Immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-2 µg/ml, incubate at RT for at least 1 hr.). Western blot (1-5 µg/ml). |
| Reactivity | Bovine, Human, Porcine |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Hybridoma produced by the fusion of splenocytes from mice immunized with full-length insulin protein and mouse myeloma cells. |
| Specificity | This antibody detects Insulin. |
| Buffer | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.08% Sodium Azide |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein A/G |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | insulin |
| Database Link | |
| Background | Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma. |
| Synonyms | INS |
| Reference Data | |
| Protein Categories | Cytokines, Diabetes, Growth Factors, Secreated Proteins |
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