Adgre1 Rat Monoclonal Antibody [Clone ID: BM8]

SKU
BM4007F
Adgre1 rat monoclonal antibody, clone BM8, FITC
$840.00
2 Weeks*
Specifications
Product Data
Clone Name BM8
Application FC, IF
Recommended Dilution Has been described to work in FACS.
Suggested Positive ControlMouse monocytes.
Reactivity Mouse
Antibody Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Cultured macrophages
Specificity This antibody recognizes the F4/80 antigen on major subpopulations of resident tissue macrophages (Schaller et al. 2002). 
Antigen Distribution
Isolated Cells: The antigen is expressed in vitro on over 80% of M-CSF stimulated bone marrow derived macrophages, after a few days of culture. It is absent from granulocytes, lymphocytes and thrombocytes.
Tissue Sections: The antigen is detected on tissue fixed macrophages in all organs tested so far (spleen, lymph nodes, thymus, liver, skin) except lung. It is also present on Langerhans cells in the skin and Kupffer cells in the liver. In complete Freund's adjuvant induced granulomas, the antigen is expressed by inflammatory macrophages, but is absent from epitheloid cells.
Buffer PBS, pH 7.2
Label: FITC
State: Liquid purified Ig fraction
Stabilizer: 10 mg/ml BSA
Preservative: 0.09% Sodium Azide
Concentration 0.1 mg/ml
Purification Affinity Chromatography
Conjugation FITC
Storage Store undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name adhesion G protein-coupled receptor E1
Database Link
Background The antigen expression increases upon maturation of macrophage precursors in bone marrow and blood as well as in ontogeny. BM8 is the only macrophage marker that is able to distinguish non-destructive from destructive inflammation processes in the pancreas and has been shown to be a unique histological marker of the progression from peri-insulitis to β-cell destruction and diabetes in a mouse diabetes model.
Synonyms Emr1, Gpf480
Reference Data
Write Your Own Review
You're reviewing:Adgre1 Rat Monoclonal Antibody [Clone ID: BM8]
Your Rating

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.