RHCE (+ CD240D) Mouse Monoclonal Antibody [Clone ID: BRIC69]
Specifications
| Product Data | |
| Clone Name | BRIC69 |
|---|---|
| Application | FC, IP |
| Recommended Dilution | Immunoprecipitation. Flow Cytometry: 10µl of the suggested working dilution to label 10e6 cells in 100µl. |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human erythrocytes |
| Specificity | This antibody recognises erythrocytes of normal Rh types but does not recognise Rhnull erythrocytes. It reacts with 31kD and 35-52kD proteins which were designated CD240DCE at the 7th leucocyte typing workshop. |
| Buffer | Tris buffered glycine, pH7.7 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | Rh blood group CcEe antigens |
| Database Link | |
| Background | The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. There are thirteen named isoforms. |
| Synonyms | Rhesus C/E antigens, Rh30A, RhIXB, Rh polypeptide 1 |
| Reference Data | |
| Protein Categories | CD Markers, Intracellular Proteins, Membrane Proteins |
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