CD44 Mouse Monoclonal Antibody [Clone ID: 156-3C11]
Specifications
| Product Data | |
| Clone Name | 156-3C11 |
|---|---|
| Application | FC, IHC, IP, WB |
| Recommended Dilution | Flow Cytometry: Use 10 µl of 1/50-1/100 diluted CD44 antibody to label 1x10e6 cells in 100 µl. Immunoprecipitation. Western Blot: Detects a band of approximately 80kDa in HeLa cell lysates. Immunohistochemistry on Frozen and Paraffin Sections: 1/100. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose. Recommneded Positive Control: Human tonsil. |
| Reactivity | Human, Monkey |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Stimulated Human leucocytes. |
| Specificity | This antibody recognises CD44, a 90kD type I transmembrane protein which is otherwise known as HCAM or CD44s. Various isoforms of CD44 exist. The 90kD standard form, recognised by this antibody, is expressed on leucocytes, erythrocytes, white matter of the brain and some epithelial cells of the breast and small intestine. Antibodies produced by clone 156-3C11 recognise epitope 3, which is a protease resistant epitope on the CD44 molecule. |
| Buffer | PBS, pH 7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG fraction |
| Concentration | lot specific |
| Purification | Affinity Chromatography on Protein G |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Gene Name | CD44 molecule (Indian blood group) |
| Database Link | |
| Background | CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. |
| Synonyms | LHR, MDU2, MDU3, MIC4, CDw44, Epican, ECMR-III, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, PGP-1 |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
