Endomucin (EMCN) Rabbit Polyclonal Antibody
$510.00
2 Weeks*
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | Western blot: 1-5 µg/ml. Immunofluorescence/Immunohistochemistry: 1-5 µg/ml (Cryo). |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Highly pure (>95%) recombinant Human soluble Endomucin (Asn18 - Ser190) derived from E. coli (Cat.-No AR31181PU-N). |
| Specificity | This antibody detects Human Endomucin (Asn18 - Ser190). Other species not tested. |
| Buffer | PBS State: Purified State: Lyophilized purified Ig fraction |
| Reconstitution Method | Restore in sterile water to a concentration of 0.1-1.0 mg/ml. Centrifuge vial prior to opening. |
| Purification | Protein A Chromatography |
| Conjugation | Unconjugated |
| Storage | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Ambient |
| Gene Name | endomucin |
| Database Link | |
| Background | Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or anti-adhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa 21 - 190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa 91 - 141, a second shows a one aa substitution for aa 91 - 129, and a third shows a one aa substitution for aa 129 - 142. Over aa 21 - 90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively. |
| Synonyms | EMCN, EMCN2, MUC14, Endomucin-2, Mucin-14, Gastric cancer antigen Ga34 |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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