BUB1B-PAK6 pSer602/560 Rabbit Polyclonal Antibody
$330.00
2 Weeks*
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | Western blot: 1:500~1:1000. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide sequence around phosphorylation site of Serine 602/560(R-K-S(p)-L-V) derived from Human PAK5/6 (KLH-conjugated) |
| Specificity | The antibody detects endogenous levels of PAK5/6 only when phosphorylated at serine 602/560. |
| Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Affinity chromatography using epitope-specific peptide |
| Conjugation | Unconjugated |
| Storage | Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 75 kDa |
| Gene Name | BUB1B-PAK6 readthrough |
| Database Link | |
| Background | This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. |
| Synonyms | p21-activated kinase 6, PAK-6 |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Intracellular Proteins |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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