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PYK2 (PTK2B) pTyr579 Rabbit Polyclonal Antibody

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SKU
AP55794PU-S
PYK2 (PTK2B) pTyr579 rabbit polyclonal antibody, Aff - Purified
Size:
50 ul 100 ul
Conjugation:
Unconjugated
  $330.00
2 Weeks*
Bulk/Customize

View other "PTK2B or NP_004094.3" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution Western blot: 1:500~1:1000.
Immunohistochemistry on paraffin sections: 1:50~1:100.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 579(E-D-Y(p)-Y-K) derived from Human PYK2 (KLH-conjugated)
Specificity The antibody detects endogenous levels of PYK2 only when phosphorylated at tyrosine 579.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 116 kDa
Gene Name protein tyrosine kinase 2 beta
Database Link
Background Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.
Synonyms PYK2, RAFTK, Protein tyrosine kinase 2 beta, Focal adhesion kinase 2, CAK-beta, CADTK
Reference Data
Protein Categories Chemokines, Enzyme: Kinases, Growth Factors, Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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