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TIE2 (TEK) pTyr992 Rabbit Polyclonal Antibody

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SKU
AP55775PU-S
TIE2 (TEK) pTyr992 rabbit polyclonal antibody, Aff - Purified
Size:
50 ul 100 ul
Conjugation:
Unconjugated
  $330.00
2 Weeks*
Bulk/Customize

View other "TEK or NP_000450.2" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution Western blot: 1:500~1:1000.
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of tyrosine 992 (E-V-Y(p)-V-K) derived from Human TIE2 (KLH-conjugated)
Specificity The Antibody detects endogenous levels of TIE2 only when phosphorylated at Tyr992.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 126 kDa
Gene Name TEK receptor tyrosine kinase
Database Link
Background The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Synonyms TIE2, TIE-2, Angiopoietin-1 receptor, p140 TEK
Reference Data
Protein Categories CD Markers, Enzyme: Kinases, Growth Factors, Membrane Proteins, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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