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PERK (EIF2AK3) pThr981 Rabbit Polyclonal Antibody

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SKU
AP55771PU-S
PERK (EIF2AK3) pThr981 rabbit polyclonal antibody, Aff - Purified
Size:
50 ul 100 ul
Conjugation:
Unconjugated
  $330.00
2 Weeks*
Bulk/Customize

View other "EIF2AK3" antibodies

Specifications
Specifications
Product Data
Application IHC
Recommended Dilution Immunohistochemistry on paraffin sections: 1:50~1:100 .
Reactivity Human, Mouse
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of threonine 981(A-R-H(p)-T-G) derived from Human PEK/PERK (KLH-conjugated)
Specificity The antibody detects endogenous levels of PEK/PERK only when phosphorylated at threonine 981.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 125 kDa
Gene Name eukaryotic translation initiation factor 2 alpha kinase 3
Database Link
Background Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1)
Synonyms PEK, PERK, HsPEK
Reference Data
Protein Categories Diabetes, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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