TOP3B (C-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB35782 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:1000 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B |
| Specificity | This TOP3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B. |
| Buffer | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 96662 kDa |
| Gene Name | topoisomerase (DNA) III beta |
| Database Link | |
| Background | This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. |
| Synonyms | TOP3B1, DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1 |
| Note | Molecular Weight: 96662 Da |
| Reference Data | |
| Protein Pathways | Homologous recombination |
Reviews
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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