ELOB (N-term) Rabbit Polyclonal Antibody

SKU
AP54200PU-N
TCEB2 Antibody (N-term)
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name RB20801
Application WB
Recommended Dilution WB 1:1000
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human TCEB2
Specificity This TCEB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-29 amino acids from the N-terminal region of human TCEB2.
Buffer PBS
State: Aff - Purified
State: Liquid Ig fraction
Preservative: 0.09% (W/V) sodium azide
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 13133 kDa
Gene Name transcription elongation factor B subunit 2
Database Link
Background This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Synonyms Elongin 18 kDa subunit, Elongin-B, Elongin B, EloB
Note Molecular Weight: 13133 Da
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Pathways in cancer, Renal cell carcinoma, Ubiquitin mediated proteolysis
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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