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TAPT1 (C-term) Rabbit Polyclonal Antibody

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SKU
AP54151PU-N
TAPT1 Antibody (C-term)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

View other "TAPT1 or NP_699196" antibodies

Specifications
Specifications
Product Data
Application FC, WB
Recommended Dilution WB:1/1000, FC:1/10-50
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 533-562 amino acids from the C-terminal region of human TAPT1
Specificity This TAPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-558 amino acids from the C-terminal region of human TAPT1.
Buffer PBS
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) sodium azide
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 64.3 kDa
Gene Name transmembrane anterior posterior transformation 1
Database Link
Background This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined.
Synonyms CMVFR, Cytomegalovirus partial fusion receptor
Reference Data
Protein Families Druggable Genome, Transmembrane
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Documents
Resources

file-alt Citations

Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations
Howell, Shindo, Murray et al
Genetics (2007) 175 (2), 699-707 DOI: 10.1534/genetics.106.065177
Cited by 37
AI Summary: OriGene products contributed to this study by providing the TAPT1 cDNA clone (OriGene: MC203267), which was used for gene expression analysis and functional studies of the Tapt1 mutation.
Cloning and epitope mapping of a functional partial fusion receptor for human cytomegalovirus gH
Baldwin, Zhang, Keay
J Gen Virol (2000) 81 (Pt 1), 27-35 DOI: 10.1099/0022-1317-81-1-27
Cited by 22
AI Summary: OriGene’s TrueClone cDNA (Cat# SC119270) was used in this study to express the CMVFR protein in MOLT-4 cells, enabling functional analysis of its role as a fusion receptor for human cytomegalovirus gH.
Molecular cloning and expression of receptor peptides that block human cytomegalovirus/cell fusion
Baldwin, Kleinberg, Keay
Biochem Biophys Res Commun (1996) 219 (2), 668-73 DOI: 10.1006/bbrc.1996.0291
Cited by 12
AI Summary: OriGene products, specifically the pGEX-4T-1 vector, were used to clone and express the receptor peptides (FR131 and FR611) that were shown to inhibit human cytomegalovirus/cell fusion in this study.
Showing 1-3 of 3 papers.
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