SYK (N-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB:1/1000 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human MID1IP1 |
| Specificity | This SYK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-305 amino acids from human SYK. |
| Buffer | PBS State: Aff - Purified State: Liquid Ig fraction Preservative: 0.09% (W/V) sodium azide |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 72.1 kDa |
| Gene Name | spleen tyrosine kinase |
| Database Link | |
| Background | This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq. |
| Synonyms | Tyrosine-protein kinase SYK, Spleen tyrosine kinase |
| Note | Molecular Weight: 72066 Da |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity |
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