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PLEKHA4 (N-term) Rabbit Polyclonal Antibody

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SKU
AP53347PU-N
PLEKHA4 Antibody (N-term)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

View other "PLEKHA4 or NP_001154826" antibodies

Specifications
Specifications
Product Data
Application FC, IHC, WB
Recommended Dilution WB:1/1000, IHC-P:1/50-200, FC:1/10-50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 28-58 amino acids from the N-terminal region of human PLEKHA4
Specificity This PLEKHA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human PLEKHA4.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 85.4 kDa
Gene Name pleckstrin homology domain containing A4
Database Link
Background PLEKHA4 binds specifically to phosphatidylinositol-3-phosphate (PtdIns3P), but not to other phosphoinositides.
Synonyms PEPP1, PEPP-1
Note Molecular Weight: 85401 Da
Reference Data
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Documents
Resources

file-alt Citations

NAT10 drives chemoresistance in AML through ac4C-dependent stabilization of PLEKHA4
Shu, Xu, Gong et al
Biochem Pharmacol (2026) 252, 118229 DOI: 10.1016/j.bcp.2026.118229
AI Summary: OriGene’s PLEKHA4 antibody (AP53347PU-N) was used in this study to detect and validate PLEKHA4 protein expression, supporting the investigation of its role in NAT10-mediated chemoresistance in AML.
Snippet: After blocking with 5% skim milk in TBST, membranes were incubated overnight at 4°C with the indicated primary antibodies against NAT10 (Abcam, USA;#ab194297), PLEKHA4 (OriGene, #AP53347PU-N), DVL2 (Abcam, USA;#ab228804), DVL3 (Abcam, USA;#ab152161)
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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