PCDHGC3 (Center) Rabbit Polyclonal Antibody

SKU
AP53216PU-N
PCDHGC3 Antibody (Center)
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name RB22247
Application FC, IHC, WB
Recommended Dilution WB 1:1000
IHC-P 1:50~100
FC 1:10~50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 511-539 amino acids from the to the central region of human PCDHGC3.
Specificity This PCDHGC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the Central region of human PCDHGC3.
Buffer PBS with 0.09% (W/V) Sodium azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 101077 kDa
Gene Name protocadherin gamma subfamily C, 3
Database Link
Background This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Synonyms Protocadherin gamma-C3, PCDH-gamma-C3, Protocadherin-2, Protocadherin 2, PCDH2, Protocadherin-43, Protocadherin 43, PC-43, PC43
Note Molecular Weight: 101077 Da
Reference Data
Protein Families Transmembrane
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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