PCDHA4 (C-term) Rabbit Polyclonal Antibody
PCDHA4 (C-term) rabbit polyclonal antibody, Aff - Purified
Product Datasheet for 'AP53198PU-N'
|Recommend Dilution||ELISA: 1/1000.
Western blot: 1/100 - 1/500.
|Immunogen||KLH conjugated synthetic peptide between 760-790 amino acids from the C-terminal region of human PCDHA4|
|Specificity||This antibody reacts to PCDHA4.|
State: Aff - Purified
State: Liquid purified Ig fraction
Preservative: 0.09% (W/V) sodium azide
|Purification||Affinity chromatography on Protein A|
|Predicted Protein Size||102293 Da|
|Gene Name||Homo sapiens protocadherin alpha 4 (PCDHA4), transcript variant 1|
|Background||This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.|
|Synonyms||Protocadherin alpha-4, PCDH-alpha-4|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.