MAML1 (Center) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB18757 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:1000 FC 1:10~50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human Mastermind-Like Protein 1 |
| Specificity | This MAML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-225 amino acids from the Central region of human MAML1. |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 108054 kDa |
| Gene Name | mastermind like transcriptional coactivator 1 |
| Database Link | |
| Background | This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. |
| Synonyms | MAML1, Mam-1 |
| Note | Molecular Weight: 108054 Da |
| Reference Data | |
| Protein Pathways | Notch signaling pathway |
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