IGSF8 (Center) Rabbit Polyclonal Antibody

SKU AP52177PU-N

IGSF8 (Center) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IHC, WB
• Recommended Dilution: Immunohistochemistry (Paraffin sections): 1/10-1/50 ; Western blotting: 1/100-1/500; ELISA: 1/1000
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide (233-262 aa) - KLH conjugated - corresponding to internal domain of human IGSF8.
• Specificity: This antibody detects IGSF8 (Center).
• Buffer: PBS with 0.09% (W/V) Sodium Azide.; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: immunoglobulin superfamily member 8
• Database Link:
  Q969P0
• Background: GSF8/PGRL/EWI-2 is a membrane protein that contains 4 Ig domains and forms highly proximal, specific and stoichiometric complexes with both CD9 and CD81 a tetraspanin. Tetraspanins and their molecular partners from primary complexes that then undergo tetraspanin-tetraspanin interactions to form a network of molecular interactions call a tetraspanin web. IGSF8 then may play a key role in diverse functions ascribed to CD81 and CD9 including oocyte fertilization or hepatitis C virus function, regulation of proliferation and differentiation of keratinocytes. It may also be a negative regulator of cell motility and suppress T-cell mobility coordinately with CD81.
• Synonyms: CD81 partner 3, LIR-D1, CD81P3, EWI2, KCT4
• Note: Molecular Weight: 65034 Da

Reference Data

• Protein Families: Transmembrane