HYAL2 (Center) Rabbit Polyclonal Antibody

SKU
AP52133PU-N
HYAL2 Antibody (Center)
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB:1/1000, IHC-P:1/50-200
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of Human HYAL2 / Hyaluronidase-2.
Specificity This HYAL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the Central region of human HYAL2.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 53.9 kDa
Gene Name hyaluronoglucosaminidase 2
Database Link
Background This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.
Synonyms LUCA2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2
Note Molecular Weight: 53860 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Glycosaminoglycan degradation, Metabolic pathways
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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