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GAS1 (N-term) Rabbit Polyclonal Antibody

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SKU
AP51781PU-N
GAS1 Antibody (N-term)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

View other "GAS1 or NP_002039" antibodies

Specifications
Specifications
Product Data
Application FC, IF, IHC, WB
Recommended Dilution WB:1/1000, IHC-P:1/50-200, IF:1/10-50, FC:1/10-50
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 102-136 amino acids from the N-terminal region of human GAS1
Specificity This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-127 amino acids from the N-terminal region of human GAS1.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 35.7 kDa
Gene Name growth arrest specific 1
Database Link
Background Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
Synonyms Growth arrest-specific protein 1, GAS-1
Note Molecular Weight: 35693 Da
Reference Data
Protein Pathways Hedgehog signaling pathway
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Documents
Resources

file-alt Citations

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
Marie, Sassano, Yang et al
Nat Commun (2020) 11 (1), 333 DOI: 10.1038/s41467-019-14085-2
Cited by 98
AI Summary: OriGene’s Myc-DDK-tagged KDELR3 transcript variant 1 construct (RC201571) was used to generate shRNA-resistant KDELR3 for functional studies, enabling the investigation of KDELR3’s role in melanoma metastasis in this study.
Snippet: Directed Mutagenesis Kit (Agilent Technologies). The KDELR3 shRNA recognition sequence was edited (t210c_c213a_t216c_t219c_a222c) from Myc-DDK-tagged KDELR3 transcript variant 1 construct (RC201571, OriGene). TOPO cloning was used to clone place this sequence into the Gateway cloning system and the pENTR L1/L2 plasmid was combined with C413-E19 pPol2 L4/R1 and pDEST-658 R4/R2 destination plasmids
FigureFigureFigure
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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