GALNT3 (Center) Rabbit Polyclonal Antibody

SKU
AP51768PU-N
GALNT3 Antibody (Center)
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application FC, IHC, WB
Recommended Dilution WB:1/1000, IHC-P:1/50-200, FC:1/10-50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 461~490 amino acids from the Center region of human GALNT3
Specificity This GALNT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the Central region of human GALNT3.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 72.6 kDa
Gene Name polypeptide N-acetylgalactosaminyltransferase 3
Database Link
Background GALNT3 encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein is highly homologous to other family members, however the enzymes have different substrate specificities.
Synonyms GalNAc transferase 3, pp-GaNTase 3, GalNAc-T3
Note Molecular Weight: 72610 Da
Reference Data
Protein Families Transmembrane
Protein Pathways Metabolic pathways, O-Glycan biosynthesis
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Documents
Resources

file-alt Citations

Exosomal circSPIRE1 mediates glycosylation of E-cadherin to suppress metastasis of renal cell carcinoma
Shu, Lu, Pan et al
Oncogene (2023) 42 (22), 1802-1820 DOI: 10.1038/s41388-023-02678-7
Cited by 52
AI Summary: OriGene products GALNT3 antibody (AP51768PU-N) and ZNF596 antibody (TA316199) were used in this study to detect protein expression levels by western blot, contributing to the investigation of the molecular mechanisms by which circSPIRE1 suppresses metastasis in renal cell carcinoma.
Snippet: …ELAVL1 contains three RRM m;anti-Flag for western blot (1:1000 dilutions, 8146, Cell Signaling), GALNT3 (1:1000 dilution, AP51768PU-N, Origene, USA), QKI (1:1000 dilution, A300-183A, BETHYL, USA), ZNF596 (1:1000 dilution, TA316199, Origene), E-cadherin (1:1000 dilution, ab40772, Abcam), N- cadherin (1:5000 dilution, ab76011, Abcam), Vimentin (1:1000 dilution, 5741, Cell Signaling), HRP-conjugated goat anti-mouse (1:5000 dilution, Proteintech, China), and HRP-conjugated goat anti-rabbit antibody (15,000 dilution, Proteintech)
WB
Showing 1-1 of 1 papers.
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