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FRG1 (C-term) Rabbit Polyclonal Antibody

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SKU
AP51724PU-N
FRG1 Antibody (C-term)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

View other "FRG1 or NP_004468" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB:1/1000
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 230-256 amino acids from the C-terminal region of Human FRG1
Specificity This FRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-256 amino acids from the C-terminal region of human FRG1.
Buffer PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 29.2 kDa
Gene Name FSHD region gene 1
Database Link
Background This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus.
Synonyms FRG1A; FSG1
Note Molecular Weight: 29172 Da
Reference Data
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Documents
Resources

file-alt Citations

Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome
Bertram, El Ayoubi, Dybkov et al
Mol Cell (2020) 80 (1), 127-139.e6 DOI: 10.1016/j.molcel.2020.09.012
Cited by 53
AI Summary: In this study, OriGene's anti-FRG1 antibody (RRID: AB_11146098) was used for immunodetection to analyze the presence and role of FRG1 protein in the human spliceosomal C complex, contributing to the structural and functional insights reported.
Snippet: … Antibodies against the following human proteins were used: SNU114 (Fabrizio et al., 1997), PRP16 (Ortlepp et al., 1998), YJU2/CCDC94 (Sigma Life Science, RRID: AB_2682880), PPWD1 (ProSci Incorporated, Catalog No: #59-425), WDR70 (Sigma Life Science, RRID: AB_2680287), FRG1 (Origene Technologies, RRID: AB_11146098), NSRP1 (Sigma Life Science, RRID: AB_2072217), CIR1 (Bethyl Laboratories, RRID: AB_10892924), RP9 (Proteintech, Catalog No: 16832-1-AP) and PPIL4 (Sigma Life Science, RRID: AB_10600928)
WB
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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