FBXW12 (C-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB27619 |
|---|---|
| Application | FC, IHC, WB |
| Recommended Dilution | WB 1:1000 IHC-P 1:50~100 FC 1:10~50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 298-328 amino acids from the C-terminal region of Human FBXW12 |
| Specificity | This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12. |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 53056 kDa |
| Gene Name | F-box and WD repeat domain containing 12 |
| Database Link | |
| Background | Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 PubMed 15520277).supplied by OMIM. |
| Synonyms | FBW12, FBXO12, FBXO35, F-box only protein 35 |
| Note | Molecular Weight: 53056 Da |
| Reference Data | |
| Protein Families | Druggable Genome |
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