Fumarylacetoacetate hydrolase (FAH) (N-term) Rabbit Polyclonal Antibody

CAT#: AP51509PU-N

Fumarylacetoacetate hydrolase (FAH) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of Fumarylacetoacetase Antibody (N-term) in HepG2 cell line lysates (35ug/lane).This demonstrates the FAH antibody detected the FAH protein (arrow).

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  Formalin fixed and paraffin embedded human liver tissue reacted with Fumarylacetoacetase Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining.

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  Confocal immunofluorescent analysis of Fumarylacetoacetase Antibody (N-term) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
  Immunofluorescence: 1/10-1/50.
  Immunohistochemistry on Paraffin Sections: 1/50-1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 14-41 amino acids from the N-terminal region of human FAH
• Specificity: This antibody recognizes Human Fumarylacetoacetase (N-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: fumarylacetoacetate hydrolase (fumarylacetoacetase)
• Database Link:
  Entrez Gene 2184 Human
  UniProt ID P16930
• Background: This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
• Synonyms: FAA, FAH, Beta-diketonase
• Note: Molecular Weight: 46374 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Tyrosine metabolism