eIF3s8 (EIF3C) (N-term) Rabbit Polyclonal Antibody

SKU AP51396PU-N

eIF3s8 (EIF3C) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: FC, IHC, WB
• Recommended Dilution: ELISA: 1/1000.; Western Blot: 1/100-1/500. ; Flow Cytometry: 1/10-1/50.; Immunohistochemistry on Paraffin Sections: 1/10-1/50.
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 127-155 amino acids from the N-terminal region of Human EIF3CL.
• Specificity: This antibody recognizes EIF3CL (N-term).
• Buffer: PBS; State: Aff - Purified; State: Liquid purified Ig fraction; Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A Chromatography followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Predicted Protein Size: 105344 Da
• Gene Name: eukaryotic translation initiation factor 3 subunit C
• Database Link:
  Q99613
• Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
• Synonyms: Eukaryotic translation initiation factor 3 subunit C, eIF3 p110

Reference Data

• Protein Families: Druggable Genome