DLL3 (C-term) Rabbit Polyclonal Antibody

CAT#: AP51274PU-N

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DLL3 (C-term) rabbit polyclonal antibody, Aff - Purified



Get 29% off any Over-Expression Cell Lysate, a validated WB control, with any Ab purchase. Use code “OEL29“. View details.

USD 465.00


Availability*
2 Weeks

Size
    • 200 ul


Product images

Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution

Immunofluorescence: 1/10-1/50.
Immunohistochemistry on Paraffin Sections: 1/50-1/100.
Western blot: 1/2000.
Enzyme immunoassay: 1/1000.

Reactivity Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 519-548 aa) of human DLL3.
Specificity This antibody recognizes DLL3 at C-term .
Formulation PBS with 0.09% (W/V) Sodium azide
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Purified through a Protein A column followed by peptide affinity purification
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens delta like canonical Notch ligand 3 (DLL3), transcript variant 1
Background Delta-like protein 3 is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.
Synonyms Delta-like protein 3, Delta-3
Note Molecular Weight: 64618 Da
Reference Data
Protein Families Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane
Protein Pathways Notch signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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