CYBA (C-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB31767 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | IF 1:10~50 WB 1:1000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 124-153 amino acids from the C-terminal region of Human Cytochrome b-245 light chain. |
| Specificity | This CYBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-145 amino acids from the C-terminal region of human CYBA. |
| Buffer | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 21013 kDa |
| Gene Name | cytochrome b-245 alpha chain |
| Database Link | |
| Background | Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. |
| Synonyms | CYBA, p22-phox, Cytochrome b558 subunit alpha |
| Note | Molecular Weight: 21013 Da |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Leukocyte transendothelial migration |
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