CYBA (C-term) Rabbit Polyclonal Antibody

SKU AP51159PU-N

CYBA (C-term) rabbit polyclonal antibody, Aff - Purified

Product Data

• Application: IF, WB
• Recommended Dilution:

  ELISA: 1/1000.; Western Blot: 1/100-1/500. ; Immunofluorescence: 1/10-1/50.

• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 124-153 amino acids from the C-terminal region of Human Cytochrome b-245 light chain.
• Specificity: This antibody recognizes Human Cytochrome b-245 light chain (C-term).
• Buffer: PBS containing 0.09% (W/V) Sodium Azide as preservative; State: Aff - Purified; State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.; Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Shipping: Blue Ice
• Gene Name: cytochrome b-245 alpha chain
• Database Link:
  P13498
• Background: Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
• Synonyms: CYBA, p22-phox, Cytochrome b558 subunit alpha
• Note: Molecular Weight: 21013 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Leukocyte transendothelial migration