CHMP6 (N-term) Rabbit Polyclonal Antibody

CAT#: AP50899PU-N

CHMP6 (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis in 293 cell line lysates (35ug/lane) using CHMP6 antibody. (N-term). This demonstrates the CHMP6 antibody detected the CHMP6 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: This antibody is suitable for Western blotting. The suggested dilution is: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 1-30aa) of human CHMP6.
• Specificity: This antibody detects human CHMP6 at N-term.
• Formulation: PBS with 0.09% (W/V) Sodium Azide.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column; followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: charged multivesicular body protein 6
• Database Link:
  Entrez Gene 79643 Human
  UniProt ID Q96FZ7
• Background: CHMP6 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PMID 16730941]).
• Synonyms: VPS20
• Note: Molecular Weight: 23485 Da

Reference Data

• Protein Pathways: Endocytosis