Bcl 7A (BCL7A) (N-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB24969 |
|---|---|
| Application | WB |
| Recommended Dilution | WB 1:1000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A |
| Specificity | This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A. |
| Buffer | PBS containing 0.09% (W/V) sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 22810 kDa |
| Gene Name | B-cell CLL/lymphoma 7A |
| Database Link | |
| Background | This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | BCL7A |
| Note | Molecular Weight: 22810 Da |
| Reference Data | |
| Protein Families | Druggable Genome |
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