SPG3A (ATL1) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50288PU-N

SPG3A (ATL1) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

ATL1 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the ATL1 antibody detected the ATL1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human ATL1
• Specificity: This antibody reacts to Atlastin-1.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: atlastin GTPase 1
• Database Link:
  Entrez Gene 51062 Human
  UniProt ID Q8WXF7
• Background: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: ATL1, GBP3, GBP-3, Spastic paraplegia 3 protein A, GTP-binding protein 3
• Note: Molecular Weight: 63544 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane