AASS (C-term) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Clone Name | RB14895 |
|---|---|
| Application | FC, WB |
| Recommended Dilution | WB 1:1000 FC 1:10~50 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human AASS. |
| Specificity | This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-834 amino acids from the C-terminal region of human AASS. |
| Buffer | PBS with 0.09% (W/V) sodium azide as preservative State: Purified State: Liquid purified Ig fraction |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Conjugation | Unconjugated |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 102132 kDa |
| Gene Name | aminoadipate-semialdehyde synthase |
| Database Link | |
| Background | This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. |
| Synonyms | LKR/SDH |
| Note | Molecular Weight: 102132 Da |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Lysine biosynthesis, Lysine degradation, Metabolic pathways |
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