ARMET (MANF) Rabbit Polyclonal Antibody

SKU
AP33453PU-N
ARMET (MANF) rabbit polyclonal antibody, Aff - Purified
  $595.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution ELISA: 1/200000.
Western Blot: 1/2000-1/6000.
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant Human MANF produced using CHO-based.
Antigen is purified from cell culture supernatant.
Specificity Recognizes Human MANF.
No cross-reactivity in MANF-knockout Mouse.
Buffer Concentrated Ammonium Sulphate in PBS pH 7.4
State: Aff - Purified
State: Liquid purified IgG fraction
Concentration lot specific
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Upon receipt, store at 2-8°C.
As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name mesencephalic astrocyte derived neurotrophic factor
Database Link
Background MANF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- induced degeneration of dopamine neurons in rodent models of Parkinson’s disease (Lindholm et al., 2008, Voutilainen et al., 2009). When administered after 6-OHDA-lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Synonyms Arginine-rich protein, MANF
Reference Data
Protein Categories Growth Factors, Secreated Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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